نتایج جستجو برای: balb/c mouse

تعداد نتایج: 280227  

Journal: :Physiology & Behavior 2015
Nathan P. Cramer Xiufen Xu Christine Christensen Alexis Bierman Clarke G. Tankersley Zygmunt Galdzicki

The interplay of environmental and genetic factors may lead to a spectrum of physiological and behavioral outcomes. How environmental stress factors interact with the diverse mouse genomes is still poorly understood and elucidating the underlying interactions requires specific stress models that can target integrated physiological systems. Here, we employ behavioral tests and whole-body plethys...

Journal: :Behavioural brain research 2011
Maria Razzoli Lucia Carboni Michela Andreoli Alice Ballottari Roberto Arban

Social stress may precipitate psychopathological disorders in susceptible individuals. The present experiments were focused on the biology beyond the differential susceptibility to social stress. Social defeat, an ethologically relevant stressor known to elicit different coping strategies, was used in two mouse strains differing for baseline emotionality, such as C57BL6/J and BalbC. In separate...

2012
Dallas C. Kinch James H. Peters Steven M. Simasko

Cholecystokinin (CCK) facilitates the process of satiation via activation of vagal afferent neurons innervating the upper gastrointestinal tract. Recent findings indicate CCK acts on these neurons via a ruthenium red (RuR) sensitive pathway that involves members of the vanilloid (V) subfamily of transient receptor potential (TRP) channels. To further test this mechanism, the mouse provides an i...

2011
Wouter Oosterlinck Annelies Vanderper Willem Flameng Paul Herijgers

We investigated glucose tolerance and left ventricular contractile performance in 4 frequently used mouse strains (Swiss, C57BL/6J, DBA2, and BalbC) at 24 weeks. Glucose tolerance was tested by measuring blood glucose levels in time after intraperitoneal glucose injection (2 mg/g body weight). Left ventricular contractility was assessed by pressure-conductance analysis. Peak glucose levels and ...

Journal: :Journal of neurophysiology 2004
Jiang Wu Neal S Peachey Alan D Marmorstein

In response to light, the retinal pigment epithelium (RPE) generates a series of slow potentials that can be recorded as the c-wave, fast oscillation (FO), and light peak (LP) of the electroretinogram (ERG). As these potentials can be related to specific cellular events, they provide information about RPE function and how that may be altered by disease or experimental manipulation. In the prese...

Journal: :American journal of physiology. Heart and circulatory physiology 2002
Coert J Zuurbier Vanessa M Emons Can Ince

This study evaluates the effects of anesthesia and fluid support on hemodynamic parameters of the mechanically ventilated mouse of four different strains. All experiments were performed at a similar surgical level of anesthesia, as indicated by the probing of the pedal withdrawal reflex. Three anesthetic regimens [fentanyl-fluanisone-midazolam (FFM), ketamine-medetomidine-atropine (KMA), and is...

2015
Wolfgang Hohenforst-Schmidt Paul Zarogoulidis Joshua Stopek Efstratios Kosmidis Thomas Vogl Bernd Linsmeier Kosmas Tsakiridis Sofia Lampaki George Lazaridis Andreas Mpakas Robert Browning Antonis Papaiwannou Antonis Drevelegas Sofia Baka Vasilis Karavasilis Ioannis Mpoukovinas J Francis Turner Konstantinos Zarogoulidis Johannes Brachmann

Novel therapies for lung cancer are being explored nowadays with local therapies being the tip of the arrow. Intratumoral chemotherapy administration and local microwave ablation have been investigated in several studies. It has been previously proposed that lipiodol has the ability to modify the microenvironment matrix. In our current study we investigated this theory in BALBC mice. In total 1...

Journal: :Genetics 2003
Russell J Butterfield Randall J Roper Dominic M Rhein Roger W Melvold Lia Haynes Runlin Z Ma R W Doerge Cory Teuscher

Susceptibility to Theiler's murine encephalomyelitis virus-induced demyelination (TMEVD), a mouse model for multiple sclerosis (MS), is genetically controlled. Through a mouse-human comparative mapping approach, identification of candidate susceptibility loci for MS based on the location of TMEVD susceptibility loci may be possible. Composite interval mapping (CIM) identified quantitative trait...

ژورنال: پژوهش در پزشکی 2013
بنده پور, مژگان, سلیمانی دارانی, معصومه, سید, نگار, شریف نیا, زرین, مصفا, نریمان, کاظمی, بهرام,

Abstract Background: Heat shock proteins, (Hsps) are used as adjuvants in vaccines these proteins induce the inflammatory cytokines and the maturation of monocyte MQ to dendritic cells. This study was done to determine the effect of Hsp90 on the immunogenicity of HbSAg in BalbC mice. Materials and methods: In this experimental study we injected Hsp90 β subunit together with HbsAg to 30 balbC mi...

2016
Helena Giannakaki-Zimmermann Despina Kokona Sebastian Wolf Andreas Ebneter Martin S. Zinkernagel

PURPOSE Optical coherence tomography angiography (OCT-A) allows noninvasive visualization of retinal vessels in vivo. OCT-A was used to characterize the vascular network of the mouse retina and was compared with fluorescein angiography (FA) and histology. METHODS In the present study, OCT-A based on a Heidelberg Engineering Spectralis system was used to investigate the vascular network in mic...

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